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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YAP1
All Species:
7.58
Human Site:
T154
Identified Species:
15.15
UniProt:
P46937
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46937
NP_006097.1
504
54462
T154
V
V
S
G
P
A
A
T
P
T
A
Q
H
L
R
Chimpanzee
Pan troglodytes
XP_001151402
488
52729
T154
V
V
S
G
P
A
A
T
P
T
A
Q
H
L
R
Rhesus Macaque
Macaca mulatta
XP_001096954
125
14040
Dog
Lupus familis
XP_536601
465
50351
W161
H
I
D
Q
T
T
T
W
Q
D
P
R
K
A
M
Cat
Felis silvestris
Mouse
Mus musculus
P46938
488
52365
A139
V
V
S
G
P
A
A
A
P
A
A
Q
H
L
R
Rat
Rattus norvegicus
Q2EJA0
469
50483
A139
G
P
A
A
T
P
A
A
Q
H
L
R
Q
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510207
422
46067
P136
Q
T
T
T
W
Q
D
P
R
K
A
M
L
S
Q
Chicken
Gallus gallus
P46936
448
47804
P153
V
V
T
G
P
G
A
P
S
S
Q
H
L
R
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001132952
442
48343
T137
P
G
W
E
M
A
K
T
P
S
G
Q
R
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q45VV3
418
46202
P136
K
A
S
I
V
Q
Q
P
D
G
Q
S
P
I
A
Honey Bee
Apis mellifera
XP_391844
511
54750
H173
P
Q
P
H
A
R
H
H
H
H
Q
K
Q
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
T201
Q
S
G
T
T
A
A
T
N
T
A
T
T
S
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
21.4
77.9
N.A.
88.6
84.9
N.A.
75.5
78.9
N.A.
73.2
N.A.
20.4
28.5
N.A.
N.A.
Protein Similarity:
100
96.8
23.6
83.3
N.A.
92.6
88.8
N.A.
79.5
81.5
N.A.
78.9
N.A.
34.5
44.4
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
86.6
6.6
N.A.
6.6
33.3
N.A.
26.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
0
13.3
N.A.
86.6
20
N.A.
20
53.3
N.A.
33.3
N.A.
13.3
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
9
42
50
17
0
9
42
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
9
0
9
9
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
9
9
9
34
0
9
0
0
0
9
9
0
0
0
0
% G
% His:
9
0
0
9
0
0
9
9
9
17
0
9
25
0
9
% H
% Ile:
0
9
0
9
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
9
0
0
0
0
0
9
0
0
9
0
9
9
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
9
0
17
25
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
17
9
9
0
34
9
0
25
34
0
9
0
9
0
0
% P
% Gln:
17
9
0
9
0
17
9
0
17
0
25
34
17
0
17
% Q
% Arg:
0
0
0
0
0
9
0
0
9
0
0
17
9
17
25
% R
% Ser:
0
9
34
0
0
0
0
0
9
17
0
9
0
25
17
% S
% Thr:
0
9
17
17
25
9
9
34
0
25
0
9
9
0
0
% T
% Val:
34
34
0
0
9
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
9
0
9
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _